Summary

Ivermectin, a large spectrum antiparasitic drug with well-stablished medical applications in dermatology (such as but not limited to rosacea/demodicosis, scabies and cutaneous larva migrans), has gained traction into public attention in the last years, being surrounded by controversies regarding its effectiveness in the treatment of COVID-19. This article aims to provide a comprehensive review of the medical uses of ivermectin in dermatology, offering a fresh and updated perspective over its mechanism of action, pharmacokinetics and its clinical applications most frequently encountered in current medical practice. Regardless of the various arguments surrounding its use in respiratory diseases, the current evidence supports the use of ivermectin as a safe and effective option in the treatment of various dermatological conditions.