Clinical cases
Progression of chronic cutaneous lupus erythematosus to systemic lupus erythematosus - a clinical case
One of the most common diseases of the connective tissue, with a big clinical and biological variety is systemic lupus erythematosus. It has a complex etiology and involve multiple organs because of the autoimmune connotations.

We present the case of a 42 years old woman , who had chronic cutaneous lupus erythematosus. This patient was
reffered to the clinic with many cutaneous lesions and with suggestive symptoms for systemic lupus erythematosus. 

At the clinical exam we found erythematosus-papulousatrophic lesions situated on the sun-exposed areas suggestive for discoid lupus erythematosus, malar rash, lupus cheilitis, erythematosus-papulous plaques on the legs specific for livedo vasculitis, acral erythematsquamous lesions with high desquamation (secondary to the Raynaud syndrom), photosensitivity and joint pain.

The patient hadn’t respect the right treatment, which led to the worsening of the disease. Considering the gravity of the lesions the patient was investigated for the posibility of appearance systemic lupus erythematosus. The laboratory findings showed positive antiRo antibodies and the presence on the pulmonary Rx of an easy thickening of the right pleura interpreted like a pahipleuritis, confirming the systemic lupus erythematosus diagnosis (ACR criteria).

After beginning the therapy with oral corticosteroid in association with Plaquenil and also topical corticosteroids the lesions were improved and the mood was better.

Furthermore the patient showed at the next internship a good evolution because of respecting the treatment and the