Clinical cases
Eruptive syringomas
Eruptive syringoma is a rare variant of syringoma, with an unclear pathogenesis which typically occurs before or during puberty.

Clinical case:
A 28-year-old female patient was examined for multiple, flat-topped, small, asymptomatic, yellowish-brown papules, localized on the face, neck and anterior chest, lesions that had been developing in successive crops in the last 3 years. There was no family history of similar eruptions. General physical examination revealed no other significant skin lesions. Histopathological examination revealed multiple short ducts and epithelial cords embedded in a fibrous stroma in dermis. The ducts were lined by two rows of epithelial cells, some with amorphous material in their lumina. According to clinical and histopathological findings, the patient was diagnosed as having eruptive syringomas.

Eruptive syringomas usually occur before or during the puberty, in successive crops, as multiple yellowish-brown small papules localizated on the face, neck, axillae, chest, abdomen,  periumbilical area or extremities. Their pathogenesis is unclear; they could represent a hyperplastic response of the eccrine ducts to an inflammatory reaction caused by Syringomas may be asociated Marfan, Ehler-Danlos or Down syndromes, neoplasms or diabetes mellitus. At present there is no satisfactory treatment for eruptive syringomas.

Eruptive syringomas are a rare variant of syringoma that must be considered in the differential diagnosis of papular dermatosis at any age.