Angiolymphoid hyperplasia with eosinophilia is a rare, benign, vascular proliferative disease of unknown etiology. This condition clinically presents as papules or subcutaneous nodules located on the head and neck, with particular predilection for the periauricular area.
Histological appearance of the angiolymphoid hyperplasia with eosinophilia is characteristic showing in the dermis an abundant proliferation of small blood vessels with protrusion of endothelial cells into the lumina, and an inflammatory infiltrate with lymphocytes and eosinophils.
Angiolymphoid hyperplasia with eosinophilia may also present the form with disseminated lesions on the head, neck, trunk and limbs.
We present the case of a 64-years old male patient with numerous dark red papules and nodules, between 2 and 8 mm in size, located on the head, neck, trunk and limbs. Histologically, in the upper and deep dermis a proliferation of capillaries occured showing protrusion of endothelial cells into the lumina, surrounded by an inflammatory infiltrate consisting predominantly of lymphocytes but also histiocytes and eosinophils, characteristic appearance of angiolymphoid hyperplasia with eosinophilia.