Objectives: Genital and anoperineal human papilloma virus (HPV) infection became one of the most common sexually transmitted diseases. HPV infection can manifest through the appearance of external genital warts or can be asymptomatic. In some cases, the HPV infection can cause different forms of cervical cancer. The aim of this study is to evaluate the number, the age and the area of origin of the patients with genital warts, who consulted the dermatologists in Mures County, Romania. Materials and methods: The data about the patients with anal-genital warts were collected from dermatologists in Mures County during 2015. Results: In 2015, 135 patients, of which 39 female and 96 male, were reported. The highest number of patients was registered for the age groups 15-24 (56 patients) and 25-34 (47 patients). The analysis of the area of origin (urban or rural) highlights a higher number of patients from the urban area (83, corresponding to 61.49% of the total), whereas only 38 patients (38.51%) originated from rural areas.