LASERs (light amplification by stimulated emission of radiation) are optical devices that generate a parallel, coherent beam of light, characterized by intensity, monochromaticity and directionality, with a narrow bandwidth and a large amount of energy. LASER devices can have different active media: liquid, solid, gaseous (diode, CO2, Argon, Alexandrite, Nd: YAG, etc.), each with a limited range of indications. The wave emitted by the Nd: YAG crystal, with a wavelength of 1064 nm, is focused on the skin and transmitted transcutaneously in a controlled way. It is then absorbed by oxyhemoglobin and transformed into thermal energy, which coagulates and subsequently destroys the target blood vessel, without affecting the overlying or perivascular tissue structures. Patients selected for LASER treatment had nodular angiomas. The parameters selected for the device emitting a wavelength of 1064 nm were: spot size of 3 or 5 mm, with a pulse duration of 10-30 ms and an energy of 160-180 J/cm2. The 100% effectiveness of this method of treating vascular lesions consisted in the complete elimination of the treated blood vessels, without long-term sequelae in all cases.