Summary

Fox-Fordyce disease is known to be a chronic and uncommon skin disease that affects regions with a high density of apocrine glands. This disease affects women between 13 and 35 years. It may be considered that hormonal imbalance play a key role in the pathogenesis, but the exact cause is still unclear.[1] Other cause may be a history of trauma caused by laser hair removal may be a trigger of this disease. Pruritus can be present and it may be caused by the extravasion of glandular content. Due to the severe itch, the patient may develop infection or hiperpigmentation in the affected regions. The clinical features are monomorphic, dome-shaped, skin-colored, follicular papules that invole the axillary, pubic, perineal and areolar areas, pruritus and hair loss in the affected regions. Histopathology is in many cases non-specific.[2] Terapeutic options are varied and may include topical steroids, topical retinoids, topical clindamycin, topical calcineurin inhibitors, oral retinoids, oral contraceptives, intradermal infiltration of botulinum toxin or triam-cinolone, excision, electrocoagulation and laser.