Summary

Pemphigoid gestationis is a rare pregnancy-specific bullous condition associated with fetal risk. Diagnosis and treatment are challenging because of the difficulties in identifying and addressing the disease and the risks associated with treatment, which often involve an individualized therapeutic approach. We present a clinical case of pemphigoid gestationis with neonatal transmission, illustrating essential aspects of diagnosis and management in a clinical context, highlighting aspects of differential diagnosis and challenges in the management of this condition.