Original articles
COMORBIDITIES RELATED TO PRURIGO NODULARIS: A DESCRIPTIVE, RETROSPECTIVE, SINGLE-CENTRE TRIAL

Summary

Introduction: Prurigo nodularis (PN) is a rare pathology characterized by hyperkeratotic, intensely pruritic nodules appearing secondary to chronic scratching, being associated with multiple pruritus-generating conditions.

Material and method: Patients diagnosed with PN in the Dermatovenereology Clinical Department of the Mureº County Clinical Hospital between January 2017 and August 2024 were included in the trial. The purpose of this trial is to evaluate the profile of patients with PN, following clinical and paraclinical data.

Results: Of the total of 26 patients diagnosed with PN, the majority were women in their 6th and 7th decades of age. All patients presented at least one chronic systemic disorder, 61.53% of them being diagnosed with various non-malignant skin disorders. By analysing the laboratory parameters, an increase in inflammatory markers, a decline in renal function and an increase in basal plasma glucose were observed in most patients.

Conclusions: The long-term follow-up of patients with this condition requires vigilance in order to identify the pathologies that accompany PN and the early institution of specialized treatment.