Summary

Introduction. Wolf’s isotopic response (WIR) refers to the occurrence of a new skin disorder exactly at the site of another, already healed and unrelated. Lichen planus (LP) is an inflammatory skin diseases considered to be triggered by various factors.

Case presentation. A 49-year-old male patient presented for a localized bullous eruption on the dorsal face of the right thigh, evolving from 15 days. Three months before he was treated in our department for herpes zoster with the same topographical distribution. Later, patient developed also oral and genital blisters. We performed the diagnosis of bullous lichen planus and we treated the patient with systemic corticotherapy successfully.

Conclusion. Our case could be considered as a patient with a predisposition for developing lichen planus in which the HVZ infection triggered the disease onset.