Summary

Autoimmune bullous dermatoses, particularly pem-phigus vulgaris (PV), are rare chronic diseases charac-terized by blisters and post-bullous erosions on the skin and mucous membranes. While genetic predisposition plays a crucial role in their development, various environmental factors, including solar radiation, medications, infections, and stress, can trigger or exacerbate the disease. This study evaluates the impact of sun exposure on the exacerbation of PV, focusing on four patients under medical care at the Dermatology and Venereology Clinic in Iaºi. These patients experienced flare-ups after prolonged sun exposure during summer months.

The study highlights UV radiation’s role in triggering PV flare-ups, with all patients showing worsened lesions after sunlight exposure. Exacerbation was observed mainly in sun-exposed areas such as the thorax, limbs, and scalp. Patients were treated with systemic corticosteroids, topical treatments, and immunosuppressive therapy, with clinical improvement noted.

The findings suggest that sun exposure, particularly during warmer months, can worsen PV symptoms. High SPF sunscreens and avoidance of direct sunlight are recommended for PV patients to minimize flare-ups. In conclusion, UV radiation and high temperatures may contribute to the increased incidence of PV exacerbations and hospitalizations, emphasizing the importance of preventive measures to reduce environmental triggers during active disease phases.