Circumscribed acral hypokeratosis is a condition
characterized by an acquired, solitary, well-defined and
depressed, asymptomatic lesion occurring in a middle-aged
or advanced-age woman. In the pathogenesis of the
condition, the existence of an aberrant epidermal clone is
incriminated as a cause of epidermal hyperproliferation and
increased corneocyte fragility.
The case presented is that of a 75-year-old patient
consulted for a clinical and histopathological lesion of
circumscribed acral hypokeratosis located at the level of the
fifth finger of the left hand. The treatment consisted of
cryotherapy without an improvement in the lesion.