Consistently use of sunscreening products has a double importance - both to avoid acute toxicity of UV radiation, to reduce long-term effect - skin aging and skin cancer. The efficiency of photoprotection products is supported by the quality of the active substances that are found in these products. Unfortunately, some of the ingredients contained in sunscreens cross the epidermis and reach the blood stream. Some products may contain ingredients that can produce significant side effects.

Oxybenzone (benzophenone-3) is a compound present in a half of photoprotection creams which could result in photosensitivity effect, carcinogenic effect, with increased production of free radicals. Inorganic agents such as zinc oxide and titanium dioxide are more safe for the sunscreening products. Zinc oxide offers better UVA protection, whereas titanium dioxide provides superior UVB protection. 

FDA (Food and Drug Administration) announced on june 2012 new rulles for sunscreen creams. Thus a product is considered waterresistant if SPF (sun protection factor) is maintained after immersion for 40 minutes (2 immersion of 20 minutes), and it is very waterresistant if maintain SPF after immersion for 80 minutes (4 immersion of 20 minutes). Only photoprotection creams with a minimum SPF 15 or higher were found to be effective in reducing the risk of skin cancer and skin aging.