Clinical trials and experimental
Bowen’s disease: Clinical, histological and immunohistochemical aspects in a series of cases
Bowen's disease (BD) or keratinocytic intraepidermal neoplasia of grade III may appear both on sun-exposed sites and on the anogenital region, being caracterised by a slow but progressive evolution. In this retrospective analysis we included 31 cases of histopathologically confirmed BD.
Both classical HE stainings (in all cases) and a series of immunohistochemical markers (in the biopsies from the anogenital region) were used and in all cases clinicopathologicalcorrelations were established.