A questionnaire-based study was undertaken to assess the impact of psoriasis on patients and discern their specific needs. The findings illustrated a significantly adverse influence of psoriasis on the quality of life, profoundly affecting daily routines, social interactions, and emotional well-being. Patients articulated explicit requirements pertaining to disease management and communication with their healthcare providers. Furthermore, the study delved into the impact of psoriasis on pre-existing medical conditions among patients. The results unveiled a substantial correlation between psoriasis and comorbidities such as depression, psoriatic arthritis, cardiovascular ailments. Notably, individuals with psoriasis exhibited a heightened prevalence of additional conditions, including anxiety, insomnia, and gastrointestinal disorders. Hence, it is imperative to develop tailored treatments, provide suitable support for psoriasis patients, and employ a multifaceted approach that considers concurrent medical conditions and vigilantly monitors the emergence of new ones onset to ameliorate their quality of life and alleviate the repercussions of this ailment.