Summary

Background: Disseminated granuloma annulare is a rare clinical variant of granuloma annulare.inflammatory skin condition with unknown etiopathogenesis.

Objective: To study clinical aspects of granuloma annulare and its relationship with coexisting pathology and therapeutic options.

Methods: We performed a retrospective study in the Craiova Dermatology Clinic on cases of patients hospitalized with disseminated granuloma annulare during 2015-2023. A total of 21 patients were evaluated and monitored for a year after initial diagnosis.

Results: We found the following associated pathology: type 2 diabetes mellitus (12 cases), dyslipidaemia (11 cases), overweight and obese (10 cases), hypothyroidism (4 cases), rheumatoid arthritis (1 case) and neoplastic disease in 4 patients. Treatment was complex and effective.

Conclusion: Patients with disseminated granuloma annulare should be investigated for internal disease.