Clinical cases
Partial unilateral lentiginosis associated with café-au-lait spots and Naevus Spilus
Partial unilateral lentiginosis (PUL) is a rare pigmentary disorder characterized by multiple lentigines that are grouped within an area of normal skin, often corresponding to one or more dermatomes, with a sharp demarcation at the midline.

Clinical case:
A 58-year-old man presented with numerous hyperpigmented macules, 0,1-0,5 cm in diameter, on the right side of his thorax and abdomen, with sharp demarcation at the midline. Also, there were several café-au-lait spots on the same location. On the superolateral aspect of the right hemithorax a few intense hyperpigmented macules and papules located on a light pigmented spot were noted. The pigmented lesions had been present since his childhood. Histopathological examination revealed typical features of lentigo. Neurological and ophthalmological examinations were normal. The diagnosis of PUL associated with cafe-au-lait spots and nevus spilus was made.

PUL may be associated with neurofibromas, café-au-lait macules and naevus acromicus, blue naevus and naevus of Ota. PUL is not associated with genetic disorders as Peutz-Jeghers syndrome or LEOPARD syndrome. PUL should be differentiated from naevus spilus. Cryotherapy and laser therapy (Q-switched ND:YAG laser) have been used in the treatment of partial unilateral lentiginosis.

PUL may be associated with others cutaneous disorders inclusively naevus spilus.