Clinical cases
Bowenoid papulosis
Bowenoid papulosis is a disease characterized by dysplastic multicentric genital papules, isolated or coalesced into plaques. The histological appearance is that of epidermoid carcinoma in situ, therefore Bowenoid papulosis may be considered an intraepithelial neoplasia. Although high-risk human papillomaviruses (HPV 16, 18, 31, 33, 39) are responsible for its etiology, most lesions are benign and regress spontaneously. The treatment of Bowenoid papulosis consists in the medical or surgical removal of the lesions. The images accompanying the text show typical Bowenoid papulosis in a male patient and a rare case of diffuse, erythroleukoplastic, pigmented Bowenoid papulosis in a female patient plus the corresponding histological image (courtesy of Professor A. Oanta, MD, PhD).